Endocrine Abstracts

In a retrospective cohort study, we reviewed the medical notes of patients with severe hyponatreaemia admitted to acute medical unit at Blackpool Hospital between January and March 2012. We assessed the severity, causes of hyponatraemia, length of stay and mortality in patients with hyponatraemia.We identified 25 patients with plasma sodium ≤120 mmol/l, 5 of whom were admitted twice during the study period. Their average age was 70 (range 30–9...

In a retrospective study, we studied the medical notes of 35 patients with adrenal insufficiency; aged 61±15 (mean ±S.D.) years. Their average age at diagnosis was 45±18 years, and duration of the disease was 17±15 years.Most patients were on hydrocortisone replacement (32 patients); taking 23±4 mg daily in divided doses, and only 3 (9%) patients were on single dose of prednisone 7.5±05 mg daily in a single do...

The aim of this retrospective study was to assess hydrocortisone replacement therapy in patients with adrenal insufficiency, by correlating hydrocortisone regimens and doses to that of serum and urine cortisol levels.Method: We studied the case notes of 83 patients, whose records contained the results of at least one valid hydrocortisone day curve and 24 h urine free cortisol level. Twenty-seven patients were on twice daily, and 56 were on thrice daily r...

Diagnosis of primary hyperparathyroidism is often made incidentally following routine biochemical screening. Parathyroidectomy is usually carried out in patients at risk of disease progression or with clinical features that may improve and that is in line with NIH guidance. Current recommendations suggest that Minimally Invasive Parathyroidectomy (MIP) should take place only if sestamibi and ultrasound findings are concordant. We studied the medical notes of 53 patients, aged ...